pentobarbital will minimize the level or result of pitolisant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Pitolisant exposure is decreased by fifty% if coadministered with powerful CYP3A4 inducers.

pentobarbital decreases amounts of toremifene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers increase amount of toremifene metabolism, lowering the steady-point out concentration in serum.

pentobarbital will minimize the level or influence of montelukast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.

pentobarbital will lower the level or effect of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.

pentobarbital will minimize the extent or influence of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.

pentobarbital will decrease the extent or outcome of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will lessen the extent or result of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will minimize the level or impact of sufentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.

pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Could bring on loss of virologic reaction and probable resistance.

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pentobarbital will minimize the extent or result of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.

Workout caution when administered to clients with acute or chronic pain; could bring about paradoxical enjoyment or significant signs or symptoms might be masked

fentanyl transdermal and pentobarbital equally maximize sedation. Keep away from or Use Alternate Drug. Limit use to sufferers for whom alternate treatment method options are inadequate

pentobarbital will decrease the level or effect of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.